Glycerol kinase + glycerol-3-phosphate dehydrogenase (hepatic)
Cofactors used
What it does, reaction by reaction
Triacylglycerol Synthesis and Lipolysis Lipid Metabolism · Cytosol / ER
Glycerol + ATP → glycerol-3-phosphate + ADP; glycerol-3-phosphate ⇌ DHAP
Converts Glycerol ATP into Glycerol-3-phosphate ADP
› Notes
Hepatic glycerol kinase and glycerol-3-phosphate dehydrogenase metabolize adipose-derived glycerol. These downstream reactions permit glycerol carbon to enter gluconeogenesis or glycolysis during fasting.
Showing all 1 reactions.
What accelerates and inhibits it
Regulation is pathway-specific, so each context is listed separately
No regulation recorded for this enzyme in the source documents.
Recent literature
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