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MS
unreviewed

Glutathione peroxidase (GPX)

1 reactions · 1 pathways

Cofactors used

Clinical / pharmacological. Selenium-dependent; principal RBC peroxide defence

What it does, reaction by reaction

1 reactions

Glutathione Metabolism (gamma-Glutamyl Cycle) Amino Acid & Nitrogen Metabolism · Cytosol

step 3 Irreversible/directional

2 GSH + H2O2 -> GSSG + 2 H2O

Converts Glutathione (GSH) H2O2 into GSSG (oxidised glutathione) H2O

Notes

Selenocysteine enzyme; the principal peroxide defence of the erythrocyte.

Showing all 1 reactions.

What accelerates and inhibits it

Regulation is pathway-specific, so each context is listed separately

0 entries

No regulation recorded for this enzyme in the source documents.

Recent literature

Europe PMC · from cache · sorted by publication date

  1. 1
    Reassigning an amber codon to selenocysteine using a functional cysteine suppression pair in <i>Escherichia coli</i>.

    Niu S, Wei J, Li M, Guo B, Yan Q, Huang Y, Jiang Z, Song J. · 2026-07-29

    unreviewed
  2. 2
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  8. 8
    Research progress of ferroptosis in gynecological diseases.

    Chen W, Zhou W, Liu S. · 2026-06-19

    open access unreviewed
  9. 9
    Synergistic application of taurine and spermidine enhances wheat tolerance to neodymium stress through redox homeostasis, metabolic adjustment, and nutrient regulation.

    Iqbal R, Mehmood H, Majeed A, Murtaza G, Rebouh NY, Alotaibi MS, Alotaibi SS, Ullah S, Huseynova A, Ali S. · 2026-06-15

    open access unreviewed
  10. 10

External claims. These come from an index outside this database and are not checked against it. Treat them as leads.