What it does, reaction by reaction
Cholesterol Biosynthesis (Mevalonate Pathway) Lipid Metabolism · Cytosol + ER
DMAPP + IPP → geranyl pyrophosphate (GPP) + PPi
Converts Dimethylallyl pyrophosphate (DMAPP) Isopentenyl pyrophosphate (IPP) into Geranyl pyrophosphate (GPP) PPi
› Notes
Geranyl pyrophosphate synthase carries out a head-to-tail prenyl transfer to form the C10 isoprenoid. Pyrophosphate release helps drive the reaction.
Showing all 1 reactions.
What accelerates and inhibits it
Regulation is pathway-specific, so each context is listed separately
No regulation recorded for this enzyme in the source documents.
Recent literature
Europe PMC · fetched just now · sorted by publication date
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1
The gut-bone axis: microbial metabolism and nutritional interventions for bone health.
Rodriguez-Bryant A, Papageorgiou M, Horcajada MN, Biver E, Ferrari S, Bonnet N. · 2026-05-22
cited 1× open access unreviewed -
2
Molecular mechanisms of folliculogenesis and oogenesis.
Ezz MA, Balboula AZ. · 2026-04-02
cited 1× open access unreviewed -
3
The role of large language models in dental diagnosis, decision-making, and communication: A systematic review.
Kaplan TT, Akyol GE. · 2026-01-27
cited 1× open access unreviewed -
4
Fracture resistance of 3D printed resin-based permanent ceramic fixed dental prostheses after thermocycling.
Ozer S, Akgun BA, Cakan U. · 2026-07-16
unreviewed -
5
Clinical performance of monolithic and veneered zirconia three-unit posterior FDPs: A five-year multicenter randomized controlled trial.
Espuelas C, María Valdés A, Bravo Palma CM, Thoma DS, Jung RE, Mühlemann S, Ioannidis A. · 2026-07-16
unreviewed -
6
Five-year outcomes of zirconia and fiber-reinforced composite cantilever inlay-retained fixed dental prostheses with different retainer designs: A randomized controlled clinical trial.
Kasem AT, Tribst JPM, Abo-Madina M, Al-Zordk W. · 2026-07-02
unreviewed -
7
Influence of thermomechanical aging on the fracture load of 3- and 4-unit fixed dental prostheses from strength and translucency gradient multilayered zirconia.
Hensel J, Eser A, Meinen J, Krolikowski S, Stawarczyk B. · 2026-07-18
unreviewed -
8
Comparing the load-bearing capacity of 3D printed and CAD/CAM milled 3Y-TZP bridges after artificial ageing.
Nold J, Spies BC, Willems E, Zhang F, Weiß F, Wesemann C, Pichotka M, Vach K, Sun J, Sandra F, Reveron H, Che… · 2026-07-13
unreviewed -
9
The CFIm25/FDPs axis orchestrates protective mitophagy in macrophages to attenuate myocardial infarction.
Zhou Y, Li Y, Liu M, Chen M, Guo H, Qi J, Han S, Yu T, Cao Y, Chen Y, Hong M. · 2026-06-18
unreviewed -
10
Preoperative Coagulation Indicators Predict Prolonged Mechanical Ventilation in Acute Type a Aortic Dissection.
Li R, Yao P, Wang J, Mei J, Liu N, Ma J, Ge Y, Zhu J. · 2026-06-11
unreviewed
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