Galactocerebrosidase (GALC)
Clinical / pharmacological. Krabbe disease
What it does, reaction by reaction
Sphingolipid Degradation (Lysosomal) Lipid Metabolism · Lysosome
Galactocerebroside -> ceramide + galactose
Converts Galactocerebroside into Ceramide Galactose
› Notes
Deficiency causes Krabbe disease (globoid cell leukodystrophy).
Showing all 1 reactions.
What accelerates and inhibits it
Regulation is pathway-specific, so each context is listed separately
No regulation recorded for this enzyme in the source documents.
Recent literature
Europe PMC · fetched just now · sorted by publication date
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1
Neonatal genetic sequencing as a first-tier option: a real-world clinical implementation study in Northern China.
Mu J, Sun M, Li Y, Li P, Zou H. · 2026-07-09
unreviewed -
2
Population-level analysis of glycoprotein glycoforms.
Toledo AG, Sorrentino JT, Schoffelen S, Voldborg B, Velasquez E, Scott AM, Larson G, Lewis NE, Malmström J. · 2026-04-30
open access unreviewed -
3
<i>Limousia</i> bacteria encode mucinolysome for mucin utilization in animal gut microbiomes.
Akresi JE, Do TVT, Cui Z, Shanmugam NRS, Moraïs S, Mizrahi I, Bayer EA, Auchtung JM, Yin Y. · 2026-03-17
open access unreviewed -
4
Mislocalisation of FLT3-ITD receptor contributes to MV4-11 leukaemia cell resistance to antibody-drug conjugate.
Nirachonkul W, Farrell MP, Tolbert TJ, Okonogi S, Tima S, Anuchapreeda S, Chiampanichayakul S, Siahaan TJ. · 2026-03-05
open access unreviewed -
5
Evaluation of antibacterial and antibiofilm activity of <i>Lacticaseibacillus</i> sp. KJK14S1 strain isolated from unexplored region of Indian Sundarbans against Gram-negative bacteria.
Santra R, Paul P, Dolui S, Roy S, Sohel S, Patra S, Biswas P, Karmakar S, Biswas K. · 2026-08-02
unreviewed -
6
Yin Yang 1 Specifically Supports the Development of Olig2 Positive Cerebellar Astrocytes.
Zarei-Kheirabadi M, Tyc KM, Dain L, Kheirabadi MA, Hanco J, Mockenhaupt K, Munir S, McQuiston A, Singh SK, Ko… · 2026-08-01
open access unreviewed -
7
Avian pathogenic Escherichia coli virulence protein Hcp2a induces incomplete autophagy in chicken HD11 cells.
Tian Y, Zhang Y, Lu L, Wang S, Dai L, Wang H, Nawaz S, Sun J, Shao Y, Wang Z, Tu J, Song X. · 2026-04-28
open access unreviewed -
8
Effects of Aspergillus sp. supplementation with or without xylanase on growth performance, nutrient digestibility, and the gastrointestinal microbiome of broilers.
Singh AK, Choi J, Ramirez GA, Guan J, Singh P, Tolstorukov I, Oakley BB, Kim WK. · 2026-04-18
open access unreviewed -
9
GALC: Guided Amplified Learning With Lipschitz Constraint for Robust Trajectory Generation.
Lin Z, Chen Z, Zhu G, Chen J, Li J. · 2026-08-01
unreviewed -
10
Globoid cell leukodystrophy (Krabbe disease).
Sinkó G, Dénes E, Farkas G, Tompa M, Kálmán B. · 2026-07-01
unreviewed
External claims. These come from an index outside this database and are not checked against it. Treat them as leads.