Galactocerebrosidase (GALC)
Clinical / pharmacological. Krabbe disease
What it does, reaction by reaction
Sphingolipid Degradation (Lysosomal) Lipid Metabolism · Lysosome
Galactocerebroside -> ceramide + galactose
Converts Galactocerebroside into Ceramide Galactose
› Notes
Deficiency causes Krabbe disease (globoid cell leukodystrophy).
Showing all 1 reactions.
What accelerates and inhibits it
Regulation is pathway-specific, so each context is listed separately
No regulation recorded for this enzyme in the source documents.
Recent literature
Europe PMC · fetched just now · sorted by publication date
-
1
Ribosome engineering enhances genetic code expansion in <i>Saccharomyces cerevisiae</i>.
Chen X, Shen W, Chen X, Zhang F, Yang B, Yue Z, Zhao G. · 2026-08-29
open access unreviewed -
2
Reassigning an amber codon to selenocysteine using a functional cysteine suppression pair in <i>Escherichia coli</i>.
Niu S, Wei J, Li M, Guo B, Yan Q, Huang Y, Jiang Z, Song J. · 2026-07-29
open access unreviewed -
3
Gut microbiomes of tribal communities in India vary with dairy and grain consumption.
Ebel ER, Kulkarni AS, Mongad DS, Olm MR, Devi SI, Mir BA, Ozarkar S, Sonnenburg ED, Shouche YS, Sonnenburg JL… · 2026-07-09
open access unreviewed -
4
Neonatal genetic sequencing as a first-tier option: a real-world clinical implementation study in Northern China.
Mu J, Sun M, Li Y, Li P, Zou H. · 2026-07-09
open access unreviewed -
5
Population-level analysis of glycoprotein glycoforms.
Toledo AG, Sorrentino JT, Schoffelen S, Voldborg B, Velasquez E, Scott AM, Larson G, Lewis NE, Malmström J. · 2026-04-30
open access unreviewed -
6
<i>Limousia</i> bacteria encode mucinolysome for mucin utilization in animal gut microbiomes.
Akresi JE, Do TVT, Cui Z, Shanmugam NRS, Moraïs S, Mizrahi I, Bayer EA, Auchtung JM, Yin Y. · 2026-03-17
cited 1× open access unreviewed -
7
Mislocalisation of FLT3-ITD receptor contributes to MV4-11 leukaemia cell resistance to antibody-drug conjugate.
Nirachonkul W, Farrell MP, Tolbert TJ, Okonogi S, Tima S, Anuchapreeda S, Chiampanichayakul S, Siahaan TJ. · 2026-03-05
open access unreviewed -
8
Acetylation‐like H2BK109Q attenuates acute brain injury and preserves axon‐myelin integrity after intracerebral hemorrhage
Jin S, Yang M, Meng J, Han Z, Rastegar‐Kashkooli Y, Lu P, Wang J, Wang J, Wu H. · 2026-10-01
open access unreviewed -
9
Renal Tubular Epithelial Cells Senescence Induced by 1‐Aminopyrene Activates Fibroblast via BRD4 Driven Senescence‐Associated Secretory Phenotype Signaling
Katarkar A, Bagde A, Maurya D, Chahare B, Mane N, Sivanesan S, Krishnamurthi K. · 2026-10-01
open access unreviewed -
10
uPAR-Targeting T Cell Engager Exerts Senolytic Effects in Mice and Non-Human Primates With Serum Aminotransferase Activity as a Safety Monitor.
Deng J, Zeng X, Guo J, Li L, Zou S, Liu N, He S, Yan L, Wang Q, Zhu Y, Wang B, Yang D, Lv L, Zhao X. · 2026-10-01
open access unreviewed
External claims. These come from an index outside this database and are not checked against it. Treat them as leads.