Skip to content
MS
Sign in
unreviewed

Fructose-bisphosphate aldolase (Aldolase A)

1 reactions · 1 pathways

What it does, reaction by reaction

1 reactions

Anaerobic Glycolysis / Lactic Acid Fermentation Energy Metabolism & Cellular Respiration · Cytosol

step 4 Reversible

Fructose-1,6-bisphosphate ⇌ glyceraldehyde-3-phosphate + dihydroxyacetone phosphate

Converts Fructose-1,6-bisphosphate into Glyceraldehyde-3-phosphate Dihydroxyacetone phosphate

› Notes

Required cofactor: none in the human class I aldolase mechanism, which uses a Schiff-base lysine intermediate. The reaction is reversible.

Showing all 1 reactions.

What accelerates and inhibits it

Regulation is pathway-specific, so each context is listed separately

0 entries

No regulation recorded for this enzyme in the source documents.

Recent literature

Refresh

Europe PMC · fetched just now · sorted by publication date

  1. 1
    The RNA binding protein ZFP36L2 displays tissue-selective mRNA targeting in mice.

    Stephenson GS, Fleifel D, Cook JG, Laederach A, Ramos SBV. · 2026-06-21

    open access unreviewed
  2. 2
    The regulatory roles of non-coding RNAs in aerobic glycolysis and therapeutic potential in pancreatic ductal adenocarcinoma.

    Fan Y, Tang X, Li S, Liu S, Fang Y, Sun X, Xue Z, Niu H, Chen Y, Dai C, Ling R. · 2026-06-09

    open access unreviewed
  3. 3
    Adipose-derived mesenchymal stem cells promote diabetic wound healing through ALDOA secretion.

    Wen J, Ye H. · 2026-05-30

    open access unreviewed
  4. 4
    Absence of autoantibodies linked to cancer and autoimmune disorders 26 weeks after BNT162b2 boosting in CoronaVac- primed individuals.

    Mat Yassim AS, Mohd Hisham AA, Mohd Rosdan BS, Tan TM, Anuar ND, Mohamed Hashim EK, Norazmi MN. · 2026-05-12

    open access unreviewed
  5. 5
    DRP1 depletion protects NK cells from hypoxia-induced dysfunction.

    Verhezen T, Van Den Eynde A, Verstraelen P, Gehrcken L, Palmiotto G, Lau HW, De Vos WH, Van Der Heijden S, Br… · 2026-02-18

    open access unreviewed
  6. 6
    Gut microbiota dysbiosis exacerbates acute pancreatitis via <i>Escherichia coli</i>-driven neutrophil heterogeneity and NETosis.

    Zou Y, Li N, Li X, Kuang M, Xu X, Guan L, Li X, Zheng P, Li L, Wan J, Lu N, Liu J, He C, Zhu Y. · 2025-12-24

    cited 2× open access unreviewed
  7. 7
    Ubiquitination-dependent regulation of ferroptosis in ischemic heart and brain.

    Zhang YY, Long XY, Tian J, Luo XJ, Peng J. · 2026-06-08

    open access unreviewed
  8. 8
    Nitric oxide-driven Warburg reprogramming at the NOS2-COX2 axis: An integrative engine of cancer hallmarks.

    Coutinho LL, Palmieri EM, Ridnour LA, Cheng RYS, Heinz WF, Anderson SK, Billiar TR, Chang J, Lockett SJ, Rang… · 2026-06-02

    open access unreviewed
  9. 9
    3D-Printable and Bioelectronic-Compatible Graphene-Reinforced PLA Nanocomposites Rejuvenate Aged Bone Regeneration Through Glycolytic Reprogramming.

    Wang M, Zhang Y, Pan H, Xu S, Zou Y, Peng Z, Jiang H, Zhu Z, Yang W, Li Y, Sun L, Hong H, Yan F. · 2026-08-13

    unreviewed
  10. 10
    Transcriptomic and Metabolomic Insights into Growth Performance of a Novel Allotriploid Fish Derived from <i>Carassius cuvieri</i>, <i>Carassius auratus</i> red var., and <i>Cyprinus carpio</i>.

    Liu F, Yang H, Liu H, Huang Z, Zhang X, Li B, Duan L, Yu J, Huang S, Liu Q, Tao M, Zhang C, Liu Q, Liu S. · 2026-08-01

    unreviewed

External claims. These come from an index outside this database and are not checked against it. Treat them as leads.