Fructose-bisphosphate aldolase (Aldolase A)
What it does, reaction by reaction
Anaerobic Glycolysis / Lactic Acid Fermentation Energy Metabolism & Cellular Respiration · Cytosol
Fructose-1,6-bisphosphate ⇌ glyceraldehyde-3-phosphate + dihydroxyacetone phosphate
Converts Fructose-1,6-bisphosphate into Glyceraldehyde-3-phosphate Dihydroxyacetone phosphate
› Notes
Required cofactor: none in the human class I aldolase mechanism, which uses a Schiff-base lysine intermediate. The reaction is reversible.
Showing all 1 reactions.
What accelerates and inhibits it
Regulation is pathway-specific, so each context is listed separately
No regulation recorded for this enzyme in the source documents.
Recent literature
Europe PMC · fetched just now · sorted by publication date
-
1
MAFF is a transcription factor that regulates contraction-induced skeletal muscle transcription.
Fukushima T, Fujioka T, Masubuchi S, Sakakibara I. · 2026-09-08
open access unreviewed -
2
The RNA binding protein ZFP36L2 displays tissue-selective mRNA targeting in mice.
Stephenson GS, Fleifel D, Cook JG, Laederach A, Ramos SBV. · 2026-06-21
open access unreviewed -
3
The regulatory roles of non-coding RNAs in aerobic glycolysis and therapeutic potential in pancreatic ductal adenocarcinoma.
Fan Y, Tang X, Li S, Liu S, Fang Y, Sun X, Xue Z, Niu H, Chen Y, Dai C, Ling R. · 2026-06-09
open access unreviewed -
4
Adipose-derived mesenchymal stem cells promote diabetic wound healing through ALDOA secretion.
Wen J, Ye H. · 2026-05-30
open access unreviewed -
5
Absence of autoantibodies linked to cancer and autoimmune disorders 26 weeks after BNT162b2 boosting in CoronaVac- primed individuals.
Mat Yassim AS, Mohd Hisham AA, Mohd Rosdan BS, Tan TM, Anuar ND, Mohamed Hashim EK, Norazmi MN. · 2026-05-12
open access unreviewed -
6
DRP1 depletion protects NK cells from hypoxia-induced dysfunction.
Verhezen T, Van Den Eynde A, Verstraelen P, Gehrcken L, Palmiotto G, Lau HW, De Vos WH, Van Der Heijden S, Br… · 2026-02-18
cited 3× open access unreviewed -
7
Gut microbiota dysbiosis exacerbates acute pancreatitis via <i>Escherichia coli</i>-driven neutrophil heterogeneity and NETosis.
Zou Y, Li N, Li X, Kuang M, Xu X, Guan L, Li X, Zheng P, Li L, Wan J, Lu N, Liu J, He C, Zhu Y. · 2025-12-24
cited 4× open access unreviewed -
8
The Maintenance of Dysmyelinated Small-Diameter Axons by 14-3-3s in the Central Nervous System.
Yamada N, Saito H, Takahashi R, Fujisato M, Hosoda Y, Sasaki B, Yamada M, Abe S, Hayashi C, Yoshimoto A, Ohka… · 2026-11-01
open access unreviewed -
9
Label-free detection of glioma radioresistance using exosomal SERS spectra and machine learning.
Wu Q, Qiu S, Lin D, Lin W, Weng Y. · 2026-07-18
unreviewed -
10
Integrating CSF and EV Proteomes Enhances Biomarker Discovery by Capturing Shared Variation Across Compartments
· 2026-10-01
open access unreviewed
External claims. These come from an index outside this database and are not checked against it. Treat them as leads.