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unreviewed

Farnesyl pyrophosphate synthase

1 reactions · 1 pathways

Cofactors used

PPi

What it does, reaction by reaction

1 reactions

Cholesterol Biosynthesis (Mevalonate Pathway) Lipid Metabolism · Cytosol + ER

step 10 Irreversible/directional

GPP + IPP → farnesyl pyrophosphate (FPP) + PPi

Converts Geranyl pyrophosphate (GPP) Isopentenyl pyrophosphate (IPP) into Farnesyl pyrophosphate (FPP) PPi

› Notes

Farnesyl pyrophosphate synthase performs the next head-to-tail condensation, forming C15 FPP. FPP is also a branch-point precursor for ubiquinone, dolichol, and protein prenylation.

Showing all 1 reactions.

What accelerates and inhibits it

Regulation is pathway-specific, so each context is listed separately

0 entries

No regulation recorded for this enzyme in the source documents.

Recent literature

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Europe PMC · from cache · sorted by publication date

  1. 1
    The gut-bone axis: microbial metabolism and nutritional interventions for bone health.

    Rodriguez-Bryant A, Papageorgiou M, Horcajada MN, Biver E, Ferrari S, Bonnet N. · 2026-05-22

    cited 1× open access unreviewed
  2. 2
    Constructing an efficient synthesis pathway in peroxisomes to boost <i>β</i>-myrcene production in yeast.

    Chang J, Wang J, Dong T, Shu Y, Wang Y, Xiao W, Yao M, Yuan Y. · 2026-04-25

    open access unreviewed
  3. 3
    Molecular mechanisms of folliculogenesis and oogenesis.

    Ezz MA, Balboula AZ. · 2026-04-02

    cited 1× open access unreviewed
  4. 4
    Computational studies deciphered the role of key genes and associated networks regulating the defense mechanism in chickpea under <i>Fusarium oxysporum</i> f. sp. <i><b>ciceris</b></i> induced wilt condition.

    Chaudhary A, Arunachalam A, Lakshmi PTV. · 2026-02-18

    open access unreviewed
  5. 5
    The role of large language models in dental diagnosis, decision-making, and communication: A systematic review.

    Kaplan TT, Akyol GE. · 2026-01-27

    cited 1× open access unreviewed
  6. 6
    Fracture resistance of 3D printed resin-based permanent ceramic fixed dental prostheses after thermocycling.

    Ozer S, Akgun BA, Cakan U. · 2026-07-16

    unreviewed
  7. 7
    Clinical performance of monolithic and veneered zirconia three-unit posterior FDPs: A five-year multicenter randomized controlled trial.

    Espuelas C, María Valdés A, Bravo Palma CM, Thoma DS, Jung RE, Mühlemann S, Ioannidis A. · 2026-07-16

    unreviewed
  8. 8
    Five-year outcomes of zirconia and fiber-reinforced composite cantilever inlay-retained fixed dental prostheses with different retainer designs: A randomized controlled clinical trial.

    Kasem AT, Tribst JPM, Abo-Madina M, Al-Zordk W. · 2026-07-02

    unreviewed
  9. 9
    A motion-activated skeletal "Pacemaker" for systemic bone remodeling via oral piezoelectric microspheres.

    Han W, Luo J, Xu Y, He X, Li X, Tan J, Wang Z, He Y, Zou P, Peng Y, Han X, Bai D, Shen J. · 2026-06-05

    open access unreviewed
  10. 10
    Influence of thermomechanical aging on the fracture load of 3- and 4-unit fixed dental prostheses from strength and translucency gradient multilayered zirconia.

    Hensel J, Eser A, Meinen J, Krolikowski S, Stawarczyk B. · 2026-07-18

    unreviewed

External claims. These come from an index outside this database and are not checked against it. Treat them as leads.