What it does, reaction by reaction
Cholesterol Biosynthesis (Mevalonate Pathway) Lipid Metabolism · Cytosol + ER
GPP + IPP → farnesyl pyrophosphate (FPP) + PPi
Converts Geranyl pyrophosphate (GPP) Isopentenyl pyrophosphate (IPP) into Farnesyl pyrophosphate (FPP) PPi
› Notes
Farnesyl pyrophosphate synthase performs the next head-to-tail condensation, forming C15 FPP. FPP is also a branch-point precursor for ubiquinone, dolichol, and protein prenylation.
Showing all 1 reactions.
What accelerates and inhibits it
Regulation is pathway-specific, so each context is listed separately
No regulation recorded for this enzyme in the source documents.
Recent literature
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