What it does, reaction by reaction
Sphingolipid Synthesis Lipid Metabolism · ER + Golgi
Dihydroceramide -> ceramide
Converts Dihydroceramide into Ceramide
› Notes
Ceramide is the hub metabolite of all complex sphingolipids and a pro-apoptotic signal.
Showing all 1 reactions.
What accelerates and inhibits it
Regulation is pathway-specific, so each context is listed separately
No regulation recorded for this enzyme in the source documents.
Recent literature
Europe PMC · fetched just now · sorted by publication date
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1
Single-cell RNA sequencing analysis of bone cancer pain model induced by Lewis lung cancer cells in male mice.
Zhou Q, Chen J, Wang H, Jin R, Paerhati H, Zhu X, Dong G, Zhang M, Jiang F. · 2026-02-27
cited 1× open access unreviewed -
2
Sphingolipid homeostasis and dysregulation in liver function and disease.
Lan J, Pan Z, Dong W, Wang J, Zhang C, Zhang Y, Wu Y, Jin J. · 2026-04-24
open access unreviewed -
3
Construction and mechanism of histone deacetylation related gene prognosis model in esophageal carcinoma.
Gu Y, Ying T, Tao K, Yang Q, Zeng J. · 2026-07-18
unreviewed -
4
Whole-exome sequencing reveals novel and previously reported variants in genes linked to white matter pathology in neurodevelopmental disorders.
Ahmad N, Aleem T, Liu C, Rashid M, Tehreem J, Junaid MAM, Asif MF, Ullah S, Ullah S, Afridi TUK, Baig UR, Tar… · 2026-07-09
unreviewed -
5
Prevalence of diabetes mellitus in long-term cancer survivors treated with craniospinal irradiation.
Richter F, Runow C, Obrecht-Sturm D, Kronziel LL, Rutkowski S, Grabow D, Denzer C, Langer T, Gebauer J. · 2026-06-13
open access unreviewed -
6
[Overexpressing NDUFA13 and CRIP1 improves B cell injury and lung Lesions in COPD mouse models].
Wang M, Lu B, Meng H, Zhou S, Mao N, Zhang Y, Lü W. · 2026-06-01
unreviewed -
7
Intracranial calcifications in DEGS1-Related Leukodystrophy: a potentially under-recognised neuroimaging feature.
Vaia Y, Kim N, Jeyasingh S, Sudhakar S, Mankad K, Biswas A, Siddiqui A, Mundy H, Hedderly T, Singh RR. · 2026-06-09
open access unreviewed -
8
Social determinants of mental health in Germany: a systematic scoping review mapping the landscape of researched determinants, outcome measures, and explanatory concepts.
Lehe MS, Reiß P, Jürgensen VC, Halbeisen G, Paslakis G. · 2026-06-04
open access unreviewed -
9
Frailty among older adults in Germany: regional variation across NAKO study centers.
König M, Rach S, Mikolajczyk R, Schöttker B, Mons U, Amthor M, Völzke H, Meinke-Franze C, Harth V, Obi N, Sch… · 2026-06-03
cited 1× open access unreviewed -
10
Validity of a seven-gene signature as a non-invasive biomarker for cirrhosis: a cross-sectional study in Egyptian patients with HBV infection.
El-Kader AA, El-Meguid MA, Zayed N, Alem SA, Barkat A, Dawood RM. · 2026-06-01
open access unreviewed
External claims. These come from an index outside this database and are not checked against it. Treat them as leads.