Enzyme or protein defect
Fructokinase
Accumulates or becomes deficient
Fructose in urine
Key features
Benign; asymptomatic
Management
None
Not clinical guidance. Written from standard clinical biochemistry, not from the uploaded documents, and marked unreviewed. Teaching-level reference for study and database seeding only. It must not be used to manage a patient.
Recent literature
Europe PMC · fetched just now · sorted by publication date
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1
Fructose: metabolic signal and modern hazard.
Johnson RJ, Lanaspa MA, Tolan DR, Goncalves MD, Softic S, Stanhope KL, Sánchez-Lozada LG, Herman MA, Rabinowi… · 2026-04-17
cited 1× unreviewed -
2
Endoplasmic reticulum stress at the forefront of fatty liver diseases and cancer.
Karin M, Kim JY. · 2025-10-14
cited 6× open access unreviewed -
3
HIF-Mediated Fructose Metabolism and Disease Progression in the Cardiovascular-Kidney-Metabolic Syndrome.
Mathew D, Davidson S, Yellon D. · 2025-08-01
cited 1× open access unreviewed -
4
Progress in Understanding the Regulation of Glucose and Fructose Metabolism.
Zhao M, Lone J, Reghupaty S, Linde-Garelli KY, Svensson KJ. · 2025-04-18
cited 1× unreviewed -
5
The interplay between nutrigenomics and low-carbohydrate ketogenic diets in personalized healthcare.
Almoghrabi YM, Eldakhakhny BM, Bima AI, Sakr H, Ajabnoor GMA, Gad HM, Mohammad FAH, Elsamanoudy SA, Awan AZ, … · 2025-06-23
cited 2× open access unreviewed -
6
Pharmacophore-based virtual screening and <i>in silico</i> investigations of small molecule library for discovery of human hepatic ketohexokinase inhibitors for the treatment of fructose metabolic disorders.
Elsaman T, Mohamed MA, Elderdery AY, Alsrhani A, Alzahrani B, Ghanem HB, Mills J, Rayzah M, Alzerwi NAN, Al-S… · 2025-04-07
cited 1× open access unreviewed -
7
Genetic heterogeneity in hereditary hearing loss: Potential role of kinociliary protein TOGARAM2.
Ramzan M, Zafeer MF, Abad C, Guo S, Owrang D, Alper O, Mutlu A, Atik T, Duman D, Bademci G, Vona B, Kalcioglu… · 2024-02-19
cited 6× unreviewed -
8
Clinical Practice Guidelines for the Diagnosis and Management of Hereditary Fructose Intolerance.
Úbeda F, Santander S, Luesma MJ. · 2024-02-23
cited 2× open access unreviewed -
9
Clinical diagnosis of genetic disorders at both single-nucleotide and chromosomal levels based on BGISEQ-500 platform.
Liu Y, Mao L, Huang H, Li W, Man J, Zhang W, Wang L, Li L, Sun Y, Zhai T, Guo X, Du L, Huang J, Li H, Wan Y, … · 2023-05-22
cited 2× open access unreviewed -
10
High Fructose Corn Syrup Accelerates Kidney Disease and Mortality in Obese Mice with Metabolic Syndrome.
Andres-Hernando A, Orlicky DJ, Cicerchi C, Kuwabara M, Garcia GE, Nakagawa T, Sanchez-Lozada LG, Johnson RJ, … · 2023-04-30
cited 12× open access unreviewed
External claims. These come from an index outside this database and are not checked against it. Treat them as leads.