Skip to content
MS
PYGM AR unreviewed

McArdle disease (GSD V)

Enzyme or protein defect

Myophosphorylase

Accumulates or becomes deficient

Muscle glycogen

Key features

Exercise intolerance, cramps, myoglobinuria, second-wind phenomenon; normal blood glucose

Management

Moderate exercise; sucrose pre-exercise

Not clinical guidance. Written from standard clinical biochemistry, not from the uploaded documents, and marked unreviewed. Teaching-level reference for study and database seeding only. It must not be used to manage a patient.

Recent literature

Nothing is fetched until you ask, so the page stays fast and the request is yours rather than automatic.

Europe PMC · ten most recent, newest first