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ABCC2 AR unreviewed

Dubin-Johnson syndrome

Bilirubin excretion

Enzyme or protein defect

MRP2 canalicular transporter

Accumulates or becomes deficient

Conjugated bilirubin

Key features

Conjugated hyperbilirubinaemia; grossly black liver

Management

Benign; reassurance

Not clinical guidance. Written from standard clinical biochemistry, not from the uploaded documents, and marked unreviewed. Teaching-level reference for study and database seeding only. It must not be used to manage a patient.

Recent literature

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Europe PMC · from cache · sorted by publication date

  1. 1
    A Rare Diagnosis of Dubin-Johnson Syndrome During Pregnancy: A Case Report.

    Mousavi SRM, Pourhasan F, Simab PA, Beikmohammadi-Gharehsaghghal S, Kaini-Shamsabadi D, Karimzadeh-Soureshjan… · 2026-08-06

    unreviewed
  2. 2
    Ileal Bile Acid Transporter Inhibitors for Symptomatic Cholestasis due to Vanishing Bile Duct Syndrome in Adults.

    Vignone A, Montecalvo D, Ferrari P, Nardelli S, Di Cola S, D'Amati G, Ascione A, Ginanni Corradini S, Parisse… · 2026-06-18

    open access unreviewed
  3. 3
    ABCC2 mutation spectrum and phenotypic diversity in pediatric Dubin-Johnson syndrome: a chinese cohort analysis.

    Wang M, Yuan W, Li J, Bi Z, Qiao C, Jiang H, Li J. · 2026-05-14

    unreviewed
  4. 4
    Dubin-Johnson and Rotor Syndromes: A Review and Update of Pathophysiological Mechanisms.

    Thakkar B, Wu GY. · 2026-04-09

    open access unreviewed
  5. 5
    Transforming Toxicity into Therapy: Exploring Bilirubin's Benefits and Its Molecular Role in Cardiac Health and Disease.

    Adenawoola MI, Kipp ZA, Hinds TD, Stec DE. · 2026-04-23

    open access unreviewed
  6. 6
    Diagnostic yield and genetic landscape of rare pediatric diseases in Vietnam identified by exome sequencing.

    Lu YT, Tran UV, Tran HT, Nguyen TL, Nguyen TM, Vu CD, Ta TA, Nguyen TT, Hoang LP, Pham AN, Vu PM, Cam PN, Dao… · 2026-04-15

    open access unreviewed
  7. 7
    Exome sequencing and analysis of 44,028 British South Asians enriched for high autozygosity.

    Kim HI, DeBoever C, Walter K, Kalantzis G, Li C, Mozaffari SV, Kundu K, Jacobs BM, Mohammadi-Shemirani P, Mus… · 2026-03-27

    cited 3× open access unreviewed
  8. 8
    A novel pathogenic variant for dubin-johnson syndrome in a case of hyperbilirubinemia and metabolic associated fatty liver disease.

    Urbani G, Burza MA, Waern J, Arnell H, Solé-Navais P, Molinaro A. · 2026-02-02

    unreviewed
  9. 9
    Genetically confirmed Dubin-Johnson syndrome presenting as long-standing isolated conjugated hyperbilirubinaemia.

    Huynh Van T, Doan LH, Nguyen Tran Tuyet T. · 2026-03-23

    unreviewed
  10. 10
    Risk Assessment for Drug-Induced Hyperbilirubinemia: A Mechanistic Approach.

    Kumar R, Kumar A, Alam A, Mundkur Y, Wingrove J. · 2026-03-01

    cited 1× open access unreviewed

External claims. These come from an index outside this database and are not checked against it. Treat them as leads.