UROD AD / acquired unreviewed
Porphyria cutanea tarda
Heme synthesis
Enzyme or protein defect
Uroporphyrinogen decarboxylase
Accumulates or becomes deficient
Uroporphyrin
Key features
Commonest porphyria; blistering photosensitivity, hypertrichosis, tea-coloured urine; linked to HCV, alcohol, iron, oestrogen
Management
Phlebotomy, low-dose hydroxychloroquine, trigger avoidance
Not clinical guidance. Written from standard clinical biochemistry, not from the uploaded documents, and marked unreviewed. Teaching-level reference for study and database seeding only. It must not be used to manage a patient.
Recent literature
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